Development of a Novel, Small-Molecule Brain-Penetrant Histone Deacetylase Inhibitor That Enhances Spatial Memory Formation in Mice-Reference-Cited by-同舟云学术

Development of a Novel, Small-Molecule Brain-Penetrant Histone Deacetylase Inhibitor That Enhances Spatial Memory Formation in Mice

Published:2022-02-08 Issue:4 Volume:65 Page:3388-3403
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Belayet Jawad B.¹,Beamish Sarah²,Rahaman Mizzanoor¹,Alanani Samer³,Virdi Rajdeep S.¹,Frick David N.¹^ORCID,Rahman A. F. M. Towheedur¹,Ulicki Joseph S.¹,Biswas Sreya³,Arnold Leggy A.¹^ORCID,Roni M. S. Rashid¹^ORCID,Cheng Eric Y.⁴^ORCID,Steeber Douglas A.³,Frick Karyn M.²,Hossain M. Mahmun¹^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry and Milwaukee Institute for Drug Discovery, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53211, United States

2. Department of Psychology, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53211, United States

3. Department of Biological Sciences, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53211, United States

4. College of Pharmacy, University of North Texas Health Science Center at Fort Worth, Fort Worth, Texas 76107, United States

Funder

Division of Chemistry

Lynde and Harry Bradley Foundation

Alzheimer's Association

University of Wisconsin-Milwaukee

Medical College of Wisconsin

National Institute of Mental Health

National Institute of General Medical Sciences

University of Wisconsin-Milwaukee Research Foundation