Mycobactin Analogues with Excellent Pharmacokinetic Profile Demonstrate Potent Antitubercular Specific Activity and Exceptional Efflux Pump Inhibition-Reference-Cited by-同舟云学术

Mycobactin Analogues with Excellent Pharmacokinetic Profile Demonstrate Potent Antitubercular Specific Activity and Exceptional Efflux Pump Inhibition

Published:2022-01-04 Issue:1 Volume:65 Page:234-256
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Shyam Mousumi¹²^ORCID,Verma Harshita²^ORCID,Bhattacharje Gourab³^ORCID,Mukherjee Piyali^ORCID,Singh Samsher^ORCID,Kamilya Sujit⁴^ORCID,Jalani Pushpendu⁵,Das Swetarka⁵^ORCID,Dasgupta Arunava⁵,Mondal Abhishake⁴^ORCID,Das Amit Kumar³,Singh Amit^ORCID,Brucoli Federico⁶^ORCID,Bagnéris Claire²^ORCID,Dickman Rachael⁷^ORCID,Basavanakatti Vinay N.⁸^ORCID,Naresh Babu Patibandla⁸^ORCID,Sankaran Vadivelan⁸^ORCID,Dev Abhimanyu¹^ORCID,Sinha Barij Nayan¹^ORCID,Bhakta Sanjib²^ORCID,Jayaprakash Venkatesan¹^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences & Technology, Birla Institute of Technology, Mesra, Ranchi 835215, Jharkhand, India

2. Mycobacteria Research Laboratory, Department of Biological Sciences, Institute of Structural and Molecular Biology, Birkbeck, University of London, Malet Street, London WC1E 7HX, U.K.

3. Department of Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur 721302, India

4. Solid State and Structural Chemistry Unit, Indian Institute of Science, CV Raman Avenue, Bangalore 560012, India

5. Microbiology Division, CSIR-Central Drug Research Institute, Sector 10 Janakipuram Extension, Sitapur Road, Lucknow 226031, India

6. Leicester School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, U.K.

7. Pharmaceutical and Biological Chemistry, UCL School of Pharmacy, University of London, London WC1N 1AX, U.K.

8. Eurofins Advinus Limited, 21 & 22, Peenya Industrial area, Bengaluru 560058, India

Funder

Science and Engineering Research Board

Global Challenges Research Fund

Department of Biotechnology , Ministry of Science and Technology

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c01349

Reference82 articles.

1. The TB epidemic from 1992 to 2002

2. WHO global progress report on tuberculosis elimination

3. Treatment and Outcome Analysis of 205 Patients with Multidrug-resistant Tuberculosis

4. Multidrug- and Extensively Drug-Resistant Tuberculosis, Germany

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