Design, Synthesis, and Biological Evaluation of 1-(Indolizin-3-yl)ethan-1-ones as CBP Bromodomain Inhibitors for the Treatment of Prostate Cancer-Reference-Cited by-同舟云学术

Design, Synthesis, and Biological Evaluation of 1-(Indolizin-3-yl)ethan-1-ones as CBP Bromodomain Inhibitors for the Treatment of Prostate Cancer

Published:2021-12-28 Issue:1 Volume:65 Page:785-810
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Xiang Qiuping¹,Wang Chao¹²,Wu Tianbang¹,Zhang Cheng¹,Hu Qingqing¹²,Luo Guolong¹²,Hu Jiankang¹²,Zhuang Xiaoxi¹,Zou Lingjiao¹,Shen Hui¹²,Wu Xishan¹,Zhang Yan¹,Kong Xiangqian³^ORCID,Liu Jinsong³^ORCID,Xu Yong¹⁴³^ORCID

Affiliation:

1. Guangdong Provincial Key Laboratory of Biocomputing, Joint School of Life Sciences, Guangzhou Institutes of Biomedicine and Health, Guangzhou Medical University, Chinese Academy of Sciences, Guangzhou 510530, China

2. University of Chinese Academy of Sciences, No. 19 Yuquan Road, Beijing 100049, China

3. State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China

4. China−New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou 510530, China

Funder

Guangdong Science and Technology Department

Ministry of Science and Technology of the People's Republic of China

Government of Guangdong Province

China Postdoctoral Science Foundation

Guangzhou Science and Technology Program key projects

National Natural Science Foundation of China

Chinese Academy of Sciences

Guangdong Provincial Key Laboratory of Biocomputing