Design of Negative and Positive Allosteric Modulators of the Cannabinoid CB2 Receptor Derived from the Natural Product Cannabidiol-Reference-Cited by-同舟云学术

Design of Negative and Positive Allosteric Modulators of the Cannabinoid CB2 Receptor Derived from the Natural Product Cannabidiol

Published:2021-06-23 Issue:13 Volume:64 Page:9354-9364
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Navarro Gemma¹²,Gonzalez Angel³,Sánchez-Morales Adrià⁴,Casajuana-Martin Nil³,Gómez-Ventura Marc⁴,Cordomí Arnau³,Busqué Félix⁴,Alibés Ramon⁴^ORCID,Pardo Leonardo³^ORCID,Franco Rafael²⁵^ORCID

Affiliation:

1. Department of Biochemistry and Physiology, Faculty of Pharmacy and Food Sciences, Universitat de Barcelona, 08028 Barcelona, Spain

2. Centro de Investigación en Red, Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, 28031 Madrid, Spain

3. Laboratory of Computational Medicine, Biostatistics Unit, Faculty of Medicine, Universitat Autònoma Barcelona, Bellaterra, 08193 Barcelona, Spain

4. Departament de Química, Universitat Autònoma de Barcelona, Bellaterra, 08193 Barcelona, Spain

5. Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, Universitat de Barcelona, 08028 Barcelona, Spain

Funder

Ministerio de Econom??a y Competitividad

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00561

Reference52 articles.

1. An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies

2. A Review of Human Studies Assessing Cannabidiol's (CBD) Therapeutic Actions and Potential

3. Sativex in the management of multiple sclerosis-related spasticity: An overview of the last decade of clinical evaluation

4. Effect of Cannabidiol on Drop Seizures in the Lennox–Gastaut Syndrome

5. Cannabinoid therapy in epilepsy

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