Development of Novel 191Pt-Labeled Hoechst33258: 191Pt Is More Suitable than 111In for Targeting DNA-Reference-Cited by-同舟云学术

Development of Novel ¹⁹¹Pt-Labeled Hoechst33258: ¹⁹¹Pt Is More Suitable than ¹¹¹In for Targeting DNA

Published:2022-03-31 Issue:7 Volume:65 Page:5690-5700
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Obata Honoka¹²³,Tsuji Atsushi B.²^ORCID,Kumata Katsushi¹,Sudo Hitomi²,Minegishi Katsuyuki¹,Nagatsu Kotaro¹,Takakura Hideo³,Ogawa Mikako³,Kurimasa Akihiro⁴,Zhang Ming-Rong¹^ORCID

Affiliation:

1. Department of Advanced Nuclear Medicine Sciences, National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan

2. Department of Molecular Imaging and Theranostics, National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan

3. Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita-ku, Sapporo, Hokkaido 060-0812, Japan

4. Division of Radiation Biology and Medicine, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, 1-15-1 Fukumuro, Miyagino-ku, Sendai, Miyagi 983-8536, Japan

Funder

Japan Society for the Promotion of Science

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c02209

Reference40 articles.

1. Biological Consequences of Radiation-induced DNA Damage: Relevance to Radiotherapy

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3. Targeting the Nucleus: An Overview of Auger-Electron Radionuclide Therapy

4. The quest to exploit the Auger effect in cancer radiotherapy – a reflective review

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