Synthetic Glycolipids as Molecular Vaccine Adjuvants: Mechanism of Action in Human Cells and In Vivo Activity-Reference-Cited by-同舟云学术

Synthetic Glycolipids as Molecular Vaccine Adjuvants: Mechanism of Action in Human Cells and In Vivo Activity

Published:2021-08-12 Issue:16 Volume:64 Page:12261-12272
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Facchini Fabio A.¹^ORCID,Minotti Alberto¹,Luraghi Andrea¹,Romerio Alessio¹,Gotri Nicole¹,Matamoros-Recio Alejandra²^ORCID,Iannucci Andrea³⁴,Palmer Charys⁵,Wang Guanbo⁶,Ingram Rebecca⁶,Martin-Santamaria Sonsoles²^ORCID,Pirianov Grisha⁵,De Andrea Marco⁴⁷,Valvano Miguel A.⁶,Peri Francesco¹^ORCID

Affiliation:

1. Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza, 2, 20126 Milano, Italy

2. Department of Structural and Chemical Biology, Centro de Investigaciones Biologicas Margarita Salas, C/Ramiro de Maeztu, 9, 28040 Madrid, Spain

3. Department of Translational Medicine, University of Eastern Piedmont, 28100 Novara, Italy

4. CAAD—Center for Translational Research on Autoimmune and Allergic Disease, University of Eastern Piedmont, 28100 Novara, Italy

5. Department of Biomedical and Forensic Sciences, Anglia Ruskin University, East Road, Cambridge CB1 1PT, U.K.

6. The Wellcome-Wolfson Institute for Experimental Medicine, Queen’s University of Belfast; 97 Lisburn Road, Belfast BT9 7BL, U.K.

7. Department of Public Health and Pediatric Sciences, University of Turin, Medical School, 10126 Turin, Italy

Funder

Ministero dell???Istruzione, dell???Universit?? e della Ricerca

Ministerio de Econom??a y Competitividad

Agencia Estatal de Investigaci??n, Ministerio de Ciencia, Innovaci??n y Universidades

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00896

Reference41 articles.

1. Key roles of adjuvants in modern vaccines

2. Innate Immune Pattern Recognition: A Cell Biological Perspective

3. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

4. Targeting C-type lectin receptors: a high-carbohydrate diet for dendritic cells to improve cancer vaccines

5. Simultaneous Targeting of Toll- and Nod-Like Receptors Induces Effective Tumor-Specific Immune Responses

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