Development of Radiohalogenated Osimertinib Derivatives as Imaging Probes for Companion Diagnostics of Osimertinib

Author:

Mishiro Kenji1ORCID,Nishii Ryuichi2,Sawazaki Izumi3,Sofuku Tomoki3,Fuchigami Takeshi3,Sudo Hitomi2,Effendi Nurmaya1,Makino Akira4ORCID,Kiyono Yasushi4,Shiba Kazuhiro5,Taki Junichi6,Kinuya Seigo6,Ogawa Kazuma13ORCID

Affiliation:

1. Institute for Frontier Science Initiative, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192, Japan

2. Institute for Quantum Medical Science, National Institutes for Quantum Science and Technology (QST) Chiba, Inage-ku, Chiba 263-8555, Japan

3. Graduate School of Medical Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192, Japan

4. Biomedical Imaging Research Center, University of Fukui, Eiheiji-cho, Yoshida-gun, Fukui 910-1193, Japan

5. Research Center for Experimental Modeling of Human Disease, Kanazawa University, Takara-machi 13-1, Kanazawa, Ishikawa 920-8640, Japan

6. Department of Nuclear Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Takara-machi 13-1, Kanazawa, Ishikawa 920-8641, Japan

Funder

Ministry of Education, Culture, Sports, Science and Technology

Terumo Foundation for Life Sciences and Arts

Kanazawa University

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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