Structure-Based Design and Synthesis of N-Substituted 3-Amino-β-Carboline Derivatives as Potent αβ-Tubulin Degradation Agents-Reference-Cited by-同舟云学术

Structure-Based Design and Synthesis of N-Substituted 3-Amino-β-Carboline Derivatives as Potent αβ-Tubulin Degradation Agents

Published:2022-01-27 Issue:3 Volume:65 Page:2675-2693
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Li Yong¹,Liu Yan¹,Zhu Zejiang¹,Yan Wei¹,Zhang Chufeng¹,Yang Zhuang¹,Bai Peng¹,Tang Minghai¹,Shi Mingsong¹,He Wen¹,Fu Suhong¹,Liu Jiang¹,Han Kai¹,Li Jiewen¹,Xie Lixin¹,Ye Haoyu¹,Yang Jianhong¹,Chen Lijuan¹^ORCID

Affiliation:

1. State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, Sichuan 610041, China

Funder

National Natural Science Foundation of China

1.3.5 project for disciplines of excellence

Sichuan Science and Technology Program

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c02159

Reference41 articles.

1. Microtubules as a target for anticancer drugs