Discovery of <i>Mycobacterium tuberculosis</i> Rv3364c-Derived Small Molecules as Potential Therapeutic Agents to Target SNX9 for Sepsis-Reference-Cited by-同舟云学术

Discovery of Mycobacterium tuberculosis Rv3364c-Derived Small Molecules as Potential Therapeutic Agents to Target SNX9 for Sepsis

Published:2022-01-04 Issue:1 Volume:65 Page:386-408
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lee Daeun¹,Lee Eunbi²³,Jang Sein¹³,Kim Kyungmin²³,Cho Euni³⁴,Mun Seok-Jun³⁴,Son Wooic¹³,Jeon Hye-In¹³,Kim Hyo Keun¹³,Jeong Young Jin¹³,Lee Yuno⁵,Oh Ji Eun⁶,Yoo Hye Hyun⁶^ORCID,Lee Youngbok²³⁷^ORCID,Min Sun-Joon²³⁷^ORCID,Yang Chul-Su¹³

Affiliation:

1. Department of Molecular and Life Science, Hanyang University, Ansan 15588, S. Korea

2. Department of Applied Chemistry, Hanyang University, Ansan 15588, S. Korea

3. Center for Bionano Intelligence Education and Research, Ansan 15588, S. Korea

4. Department of Bionano Technology, Hanyang University, Seoul 04673, S. Korea

5. Korea Chemical Bank, Korea Research Institute of Chemical Technology, Daejeon 34114, S. Korea

6. Institute of Pharmaceutical Science and Technology and College of Pharmacy, Hanyang University, Ansan 15588, S. Korea

7. Department of Chemical & Molecular Engineering, Hanyang University, Ansan 15588, S. Korea

Funder

National Research Foundation of Korea

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c01551

Reference42 articles.

1. Inhibition of the Plasma-Membrane-Associated Serine Protease Cathepsin G by Mycobacterium tuberculosis Rv3364c Suppresses Caspase-1 and Pyroptosis in Macrophages

2. Mycobacterium tuberculosis Rv2626c‐derived peptide as a therapeutic agent for sepsis

3. Multi-Functional MPT Protein as a Therapeutic Agent against Mycobacterium tuberculosis

4. Peptides or Small Molecules? Different Approaches to Develop More Effective CDK Inhibitors

5. Genome wide approaches discover novel Mycobacterium tuberculosis antigens as correlates of infection, disease, immunity and targets for vaccination

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