Gut-Restricted Selective Cyclooxygenase-2 (COX-2) Inhibitors for Chemoprevention of Colorectal Cancer-Reference-Cited by-同舟云学术

Gut-Restricted Selective Cyclooxygenase-2 (COX-2) Inhibitors for Chemoprevention of Colorectal Cancer

Published:2021-07-19 Issue:15 Volume:64 Page:11570-11596
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhang Zhuming¹^ORCID,Ghosh Avijit²,Connolly Peter J.¹,King Peter²,Wilde Thomas²,Wang Jianyao²^ORCID,Dong Yawei³,Li Xueliang³,Liao Daohong³,Chen Hao³,Tian Gaochao⁴,Suarez Javier⁴,Bonnette William G.⁴,Pande Vineet⁵,Diloreto Karen A.²,Shi Yifan²,Patel Shefali²,Pietrak Beth⁴,Szewczuk Lawrence⁴,Sensenhauser Carlo²,Dallas Shannon²,Edwards James P.¹,Bachman Kurtis E.⁶,Evans David C.²

Affiliation:

1. Discovery Chemistry, Janssen Research and Development, Spring House, Pennsylvania 19477, United States

2. Drug Metabolism and Pharmacokinetics, Janssen Research and Development, Spring House, Pennsylvania 19477, United States

3. Chemistry, Pharmaron Beijing, Co. Ltd., No. 6, TaiHe Road, BDA Beijing 100176, P. R. China

4. Discovery Technology and Molecular Pharmacology, Janssen Research and Development, Spring House, Pennsylvania 19477, United States

5. Discovery Chemistry, Janssen Research and Development, Turnhoutseweg 30, B-2340 Beerse, Belgium

6. Oncology Discovery, Janssen Research and Development, Spring House, Pennsylvania 19477, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00890

Reference69 articles.

1. Cancer Statistics, 2021

2. A genetic model for colorectal tumorigenesis

3. From Gut Homeostasis to Cancer

4. Chemoprevention of hereditary colon cancers: time for new strategies

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