Design, Synthesis, Biological Evaluation, and Computational Studies of Novel Ureidopropanamides as Formyl Peptide Receptor 2 (FPR2) Agonists to Target the Resolution of Inflammation in Central Nervous System Disorders-Reference-Cited by-同舟云学术

Design, Synthesis, Biological Evaluation, and Computational Studies of Novel Ureidopropanamides as Formyl Peptide Receptor 2 (FPR2) Agonists to Target the Resolution of Inflammation in Central Nervous System Disorders

Published:2022-03-08 Issue:6 Volume:65 Page:5004-5028
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Mastromarino Margherita¹,Favia Maria¹,Schepetkin Igor A.²,Kirpotina Lylia N.²,Trojan Ewa³,Niso Mauro¹,Carrieri Antonio¹^ORCID,Leśkiewicz Monika³,Regulska Magdalena³,Darida Massimiliano⁴,Rossignolo Francesco⁴,Fontana Stefano⁴,Quinn Mark T.²^ORCID,Basta-Kaim Agnieszka³,Leopoldo Marcello¹^ORCID,Lacivita Enza¹^ORCID

Affiliation:

1. Dipartimento di Farmacia−Scienze del Farmaco, Università degli Studi di Bari Aldo Moro, via Orabona, 4, 70125 Bari, Italy

2. Department of Microbiology and Cell Biology, Montana State University, Bozeman, Montana 59717, United States

3. Laboratory of Immunoendocrinology, Department of Experimental Neuroendocrinology, Maj Institute of Pharmacology, Polish Academy of Sciences, 12 Smȩtna St., 31-343 Kraków, Poland

4. Aptuit Srl, an Evotec Company, Via A. Fleming, 4, 37135 Verona, Italy

Funder

National Institute of Food and Agriculture

Alzheimer's Association

Narodowe Centrum Nauki

National Institutes of Health

Montana State University

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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