Rational Design of Original Fused-Cycle Selective Inhibitors of Tryptophan 2,3-Dioxygenase-Reference-Cited by-同舟云学术

Rational Design of Original Fused-Cycle Selective Inhibitors of Tryptophan 2,3-Dioxygenase

Published:2021-08-02 Issue:15 Volume:64 Page:10967-10980
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kozlova Arina¹²³,Thabault Léopold¹⁴^ORCID,Liberelle Maxime¹,Klaessens Simon²³,Prévost Julien R. C.¹^ORCID,Mathieu Caroline¹,Pilotte Luc²³^ORCID,Stroobant Vincent²³,Van den Eynde Benoît²³⁵,Frédérick Raphaël¹^ORCID

Affiliation:

1. Louvain Drug Research Institute (LDRI), Université Catholique de Louvain (UCLouvain), Brussels B-1200, Belgium

2. Ludwig Institute for Cancer Research, Brussels B-1200, Belgium

3. de Duve Institute, UCLouvain, Brussels B-1200, Belgium

4. Pole of Pharmacology and Therapeutics, Institut de Recherche Expérimentale et Clinique (IREC), UCLouvain, Brussels B-1200, Belgium

5. Walloon Excellence in Life Sciences and Biotechnology, Brussels B-1200, Belgium

Funder

FÃ©dÃ©ration Wallonie-Bruxelles

Fonds Joseph Maisin

Fonds De La Recherche Scientifique - FNRS

Stichting Tegen Kanker

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00323

Reference50 articles.

1. Mechanisms of Resistance to Immune Checkpoint Blockade: Why Does Checkpoint Inhibitor Immunotherapy Not Work for All Patients?

2. Patterns of failure after immunotherapy with checkpoint inhibitors predict durable progression-free survival after local therapy for metastatic melanoma

3. The Next Generation of Immunotherapy for Cancer: Small Molecules Could Make Big Waves

4. Opportunities for Small Molecules in Cancer Immunotherapy

5. Recent advances in small molecule based cancer immunotherapy

Cited by 15 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Heme-based dioxygenases: Structure, function and dynamics;Journal of Inorganic Biochemistry;2024-12

2. Structural modification strategies of triazoles in anticancer drug development;European Journal of Medicinal Chemistry;2024-09

3. Cheminformatics analysis of indoleamine and tryptophan 2,3-dioxygenase inhibitors: A descriptor and fingerprint based machine learning approach to disclose selectivity measures;Computers in Biology and Medicine;2024-09

4. Structural Insights into Protein-Inhibitor Interactions in Human Tryptophan Dioxygenase;Journal of Medicinal Chemistry;2024-08-06

5. An update on lipophilic efficiency as an important metric in drug design;Expert Opinion on Drug Discovery;2024-06-26