Synthesis and Evaluation of PPARδ Agonists That Promote Osteogenesis in a Human Mesenchymal Stem Cell Culture and in a Mouse Model of Human Osteoporosis-Reference-Cited by-同舟云学术

Synthesis and Evaluation of PPARδ Agonists That Promote Osteogenesis in a Human Mesenchymal Stem Cell Culture and in a Mouse Model of Human Osteoporosis

Published:2021-05-14 Issue:10 Volume:64 Page:6996-7032
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kress Brian J.¹^ORCID,Kim Dong Hyun²³,Mayo Jared R.¹,Farris Jeffery T.¹,Heck Benjamin³⁴,Sarver Jeffrey G.¹,Andy Divya¹,Trendel Jill A.¹,Heck Bruce E.³,Erhardt Paul W.¹

Affiliation:

1. Center for Drug Design and Development, Department of Medicinal and Biological Chemistry, University of Toledo College of Pharmacy and Pharmaceutical Sciences, 3000 Arlington Avenue, Toledo, Ohio 43614, United States

2. Sungkyunkwan University School of Medicine, Seoul 16419, Republic of Korea

3. Northwest Ohio Stem Cure LLC, Northwest Ohio Orthopedics & Sports Medicine, Inc., Findlay, Ohio 45840, United States

4. Bluffton University, Bluffton, Ohio 45817, United States

Funder

National Research Foundation of Korea

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00560