Structural Optimization and Structure–Activity Relationship of 1<i>H</i>-Pyrazole-4-carboxylic Acid Derivatives as DNA 6mA Demethylase ALKBH1 Inhibitors and Their Antigastric Cancer Activity-Reference-Cited by-同舟云学术

Structural Optimization and Structure–Activity Relationship of 1H-Pyrazole-4-carboxylic Acid Derivatives as DNA 6mA Demethylase ALKBH1 Inhibitors and Their Antigastric Cancer Activity

Published:2024-09-03 Issue:17 Volume:67 Page:15456-15475
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Li Feng¹²,Xiong Liang¹²^ORCID,Zhang Jian¹²,Guo Yinping¹²,Xu Ke³,Xiong Zijie¹²,Wang Yuyang¹²,Ji Shanmian³,Tong Aiping¹,Li Linli³^ORCID,Yang Shengyong¹²^ORCID

Affiliation:

1. Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China

2. New Cornerstone Science Laboratory, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China

3. Key Laboratory of Drug Targeting and Drug Delivery System of Ministry of Education, West China School of Pharmacy, Sichuan University, Chengdu, Sichuan 610041, China

Funder

Sichuan University

West China Hospital, Sichuan University

National Key Research and Development Program of China

China Postdoctoral Science Foundation

Fundamental Research Funds for the Central Universities

National Natural Science Foundation of China

Sichuan Provincial Science and Technology Support Program

New Cornerstone Science Foundation

Frontiers Medical Center, Tianfu Jincheng Laboratory Foundation

Guangzhou National Laboratory

Publisher