Discovery of Novel Ortho-Aminophenol Derivatives Targeting Lipid Peroxidation with Potent Antiferroptotic Activities

Author:

Sheng Xie-Huang1ORCID,Han Li-Cong1,Gong Ao2,Meng Xiang-Shuai1,Wang Xin-Hui1,Teng Lin-Song3,Sun Xiao-Han1,Xu Kuo-Chen3,Liu Zhao-Hua4,Wang Ting5ORCID,Ma Jian-Ping1ORCID,Zhang Lei3ORCID

Affiliation:

1. College of Chemistry, Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Provincial Key Laboratory of Clean Production of Fine Chemicals, Shandong Normal University, Jinan 250014, China

2. Second Clinical Medical College of Shandong University of Traditional Chinese Medicine, Jinan 250001, China

3. Department of Orthopedic Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Tissue Engineering Laboratory, Department of Radiology, Shandong First Medical University, Shandong Key Laboratory of Rheumatic Disease and Translational Medicine, Jinan 250014, China

4. The Model Animal Research Center, Cheeloo College of Medicine, Shandong University, Jinan 250014, China

5. Department of Obstetrics and Gynecology, The First Affiliated Hospital of Shandong First Medical University, Jinan 250014, China

Funder

Shandong University

Natural Science Foundation of Shandong Province

Shandong normal unviersity Undergraduates? Innovation and Entrepreneurship Training Program

Publisher

American Chemical Society (ACS)

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