Genomic Discovery and Structure–Activity Exploration of a Novel Family of Enzyme-Activated Covalent Cyclin-Dependent Kinase Inhibitors-Reference-Cited by-同舟云学术

Genomic Discovery and Structure–Activity Exploration of a Novel Family of Enzyme-Activated Covalent Cyclin-Dependent Kinase Inhibitors

Published:2024-07-30 Issue:15 Volume:67 Page:13147-13173
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Davison Jack R.¹^ORCID,Hadjithomas Michalis¹,Romeril Stuart P.¹,Choi Yoon Jong¹,Bentley Keith W.¹,Biggins John B.¹,Chacko Nadia¹,Castaldi M. Paola¹,Chan Lawrence K.¹,Cumming Jared N.¹,Downes Thomas D.¹,Eisenhauer Eric L.¹^ORCID,Fei Fan¹,Fontaine Benjamin M.¹,Endalur Gopinarayanan Venkatesh¹^ORCID,Gurnani Srishti¹^ORCID,Hecht Audrey¹,Hosford Christopher J.¹,Ibrahim Ashraf¹,Jagels Annika¹,Joubran Camil¹,Kim Ji-Nu¹,Lisher John P.¹,Liu Daniel D.¹,Lyles James T.¹^ORCID,Mannara Matteo N.¹^ORCID,Murray Gordon J.¹,Musial Emilia¹^ORCID,Niu Mengyao¹,Olivares-Amaya Roberto¹^ORCID,Percuoco Marielle¹,Saalau Susanne¹,Sharpe Kristen¹,Sheahan Anjali V.¹,Thevakumaran Neroshan¹,Thompson James E.¹,Thompson Dawn A.¹,Wiest Aric¹,Wyka Stephen A.¹,Yano Jason¹,Verdine Gregory L.¹²^ORCID

Affiliation:

1. LifeMine Therapeutics, 30 Acorn Park Drive, Cambridge, Massachusetts 02140, United States

2. Departments of Chemistry and Chemical Biology, and Stem Cell and Regenerative Biology, Harvard University and Harvard Medical School, 12 Oxford Street, Cambridge, Massachusetts 02138, United States

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c01095

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