Synthesis and Biological Evaluation of Pyrazole–Pyrimidones as a New Class of Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Synthesis and Biological Evaluation of Pyrazole–Pyrimidones as a New Class of Correctors of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)

Published:2024-08-13 Issue:16 Volume:67 Page:13891-13908
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Vaccarin Christian¹²,Veit Guido³,Hegedus Tamas⁴⁵,Torres Odalys⁴,Chilin Adriana¹,Lukacs Gergely L.³,Marzaro Giovanni¹^ORCID

Affiliation:

1. Department of Pharmaceutical and Pharmacological Sciences, University of Padova, 35131 Padova, Italy

2. Center for Radiopharmaceutical Sciences, ETH-PSI-USZ, Paul Scherrer Institute, 5232 Villigen, Switzerland

3. Department of Physiology and Biochemistry, McGill University, Montréal, QC H3G 1Y6, Canada

4. Institute of Biophysics and Radiation Biology, Semmelweis University, 1085 Budapest, Hungary

5. HUN-REN Biophysical Virology Research Group, Hungarian Research Network, Budapest 1052, Hungary

Funder

Canadian Institutes of Health Research

Fondazione per la Ricerca sulla Fibrosi Cistica

Cystic Fibrosis Canada

Cystic Fibrosis Foundation

Università degli Studi di Padova

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c00685

Reference65 articles.

1. Cystic fibrosis

2. CFTR Modulators: Shedding Light on Precision Medicine for Cystic Fibrosis

3. Structure and Function of the CFTR Chloride Channel

4. Cystic fibrosis genetics: from molecular understanding to clinical application

5. Genetics of cystic fibrosis: CFTR mutation classifications toward genotype-based CF therapies

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP