Restoration of the Lost Human Beta Defensin-1 Protein in Cancer as a Strategy to Improve the Efficacy of Chemotherapy-Reference-Cited by-同舟云学术

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Restoration of the Lost Human Beta Defensin-1 Protein in Cancer as a Strategy to Improve the Efficacy of Chemotherapy

Published:2024-08-13 Issue:16 Volume:67 Page:14200-14209
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pandurangi Raghu¹^ORCID,Sekar Thillai²,Paulmurugan Ramasamy²^ORCID

Affiliation:

1. President, CSO, Sci-Engi-Medco Solutions Inc. (SEMCO), 573, Lexington Landing Pl, St Charles, 2, St Charles, Missouri 63303, United States

2. Molecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University School of Medicine, 3155 Porter Drive, Room: 2236, Palo Alto, California 94304, United States

Funder

National Institute of Health Sciences

Sci-Engi-Medco Solutions Inc

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c01040

Reference26 articles.

1. Functional analysis of the host defense peptide Human Beta Defensin-1: New insight into its potential role in cancer

2. Evading apoptosis in cancer

3. Cancer-Specific Loss of β-Defensin 1 in Renal and Prostatic Carcinomas

4. cPandurangi, R., Compositions and methods for sensitizing low-responsive tumors to cancer therapy. U.S. Patent 11, 957, 732B, 2024.

5. Deficient activation of the CD95 (APO-1/Fas) system in drug-resistant cells

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