Design, Synthesis, Formulation, and Bioevaluation of Trisubstituted Triazines as Highly Selective mTOR Inhibitors for the Treatment of Human Breast Cancer-Reference-Cited by-同舟云学术

Design, Synthesis, Formulation, and Bioevaluation of Trisubstituted Triazines as Highly Selective mTOR Inhibitors for the Treatment of Human Breast Cancer

Published:2024-04-25 Issue:9 Volume:67 Page:7330-7358
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Sun Qiwen¹,Chu Yuxiu²,Zhang Nana¹,Chen Rui¹,Wang Lili¹,Wu Jiangxia³,Dong Yongxi¹,Li Hongliang⁴,Wang Ling³^ORCID,Tang Lei¹,Zhan Changyou²^ORCID,Zhang Ji-Quan¹^ORCID

Affiliation:

1. Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, College of Pharmacy, Guizhou Medical University, Guiyang 561113, P. R. China

2. Department of Pharmacy, Shanghai Pudong Hospital & Department of Pharmacology, School of Basic Medical Sciences, Fudan University, Shanghai 200032, P. R. China

3. School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, P. R. China

4. School of Medicine, Yunnan University, 2 Cuihu North Road, Kunming 650091, China

Funder

Natural Science Foundation of Guizhou Province

Guizhou Medical University

National Natural Science Foundation of China

Guizhou Provincial Excellent Young Talents Plan

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c00173

Reference42 articles.