A Virtual Drug Discovery Screening Illuminates Campesterol as a Potent Estrogen Receptor Alpha Inhibitor in Breast Cancer-Reference-Cited by-同舟云学术

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A Virtual Drug Discovery Screening Illuminates Campesterol as a Potent Estrogen Receptor Alpha Inhibitor in Breast Cancer

Published:2024-06-05 Issue:12 Volume:67 Page:10321-10335
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Majumder Ranabir¹,Banerjee Shreya¹,Mandal Madhurima¹,Patra Sucharita¹,Das Subhasis²,Mandal Mahitosh¹^ORCID

Affiliation:

1. Cancer Biology Lab, School of Medical Science and Technology, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal 721302, India

2. Patient-Derived Models Lab, University of Illinois Cancer Center and Department of Surgery, College of Medicine, University of Illinois at Chicago, Chicago,Illinois 60612, United States

Funder

Indian Council of Medical Research

Council of Scientific and Industrial Research, India

Science and Engineering Research Board

Indian Institute of Technology Kharagpur

Ministry of Education, India

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c00766

Reference40 articles.

1. Understanding breast cancer as a global health concern

2. Metastatic heterogeneity of breast cancer: Molecular mechanism and potential therapeutic targets

3. A Basic Review on Estrogen Receptor Signaling Pathways in Breast Cancer

4. The Structural Basis of Estrogen Receptor/Coactivator Recognition and the Antagonism of This Interaction by Tamoxifen

5. Multidomain architecture of estrogen receptor reveals interfacial cross-talk between its DNA-binding and ligand-binding domains

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