Discovery of Novel Antiosteoporosis Leads with Bone Resorption Inhibition and Anabolic Promotion through a Chemotype-Assembly Approach-Reference-Cited by-同舟云学术

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Discovery of Novel Antiosteoporosis Leads with Bone Resorption Inhibition and Anabolic Promotion through a Chemotype-Assembly Approach

Published:2024-08-21 Issue:17 Volume:67 Page:15311-15327
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Huang Dane¹^ORCID,Zhao Chao²³^ORCID,Li Ruyue⁴,Yao Nan¹^ORCID,Xu Jun²^ORCID,Gu Qiong²^ORCID

Affiliation:

1. Guangdong Provincial Key Laboratory of Research and Development in Traditional Chinese Medicine, Guangdong Provincial Second Hospital of Traditional Chinese Medicine (Guangdong Provincial Engineering Technology Research Institute of Traditional Chinese Medicine), Guangzhou 510095, China

2. Research Center for Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China

3. Cell Inspire Therapeutics Co., Ltd., Shenzhen 518101, China

4. Department of Pharmacy, People’s Hospital of Zhengzhou, Zhengzhou 450053, China

Funder

Guangzhou Municipal Science and Technology Project

National Natural Science Foundation of China

Basic and Applied Basic Research Foundation of Guangdong Province

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c00909

Reference42 articles.

1. A microtomographic system for the nondestructive evaluation of bone architecture

2. Osteoporosis treatment: recent developments and ongoing challenges

3. A broader strategy for osteoporosis interventions

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