A β-Carboline Derivate PAD4 Inhibitor Reshapes Neutrophil Phenotype and Improves the Tumor Immune Microenvironment against Triple-Negative Breast Cancer

Author:

Zhu Di12ORCID,Lu Yu12,Yan Zhanchao3,Deng Qian12,Hu Bo12,Wang Yinsong4ORCID,Wang Wenjing5,Wang Yanming3,Wang Yuji126ORCID

Affiliation:

1. Department of Medicinal Chemistry, College of Pharmaceutical Sciences of Capital Medical University, Beijing 100069, P. R. China

2. Beijing Area Major Laboratory of Peptide and Small Molecular Drugs, Engineering Research Center of Endogenous Prophylactic of Ministry of Education of China, Beijing Laboratory of Biomedical Materials, Beijing 100069, P. R. China

3. The First Affiliated Hospital of Henan University, Center for Clinical Research and Translational Medicine, Laboratory of Epigenetics, Henan University, Kaifeng 475004, P. R. China

4. The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin 300070, P. R. China

5. Beijing Institute of Hepatology, Beijing Youan Hospital, Capital Medical University, Beijing 100069, P. R. China

6. Beijing Laboratory of Oral Health, Capital Medical University, Beijing 100069, P. R. China

Funder

China Scholarship Council

Beijing Laboratory of Oral Health

Beijing Municipal Colleges and Universities High Level Talents Introduction and Cultivate Project???Beijing Great Wall Scholar Program

Capital Medical University Scientific Research Cultivating Fund

Publisher

American Chemical Society (ACS)

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Peptidylarginine deiminase (PAD): A promising target for chronic diseases treatment;International Journal of Biological Macromolecules;2024-10

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