Discovering New Metallo-Deubiquitinase CSN5 Inhibitors by a Non-Catalytic Activity Assay Platform-Reference-Cited by-同舟云学术

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Discovering New Metallo-Deubiquitinase CSN5 Inhibitors by a Non-Catalytic Activity Assay Platform

Published:2024-08-12 Issue:16 Volume:67 Page:14649-14667
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Yan Yu-Hang¹,Wei Liu-Liu¹,Wu Jing-Wei¹,Wei Si-Qi¹,Jiang Ying-Ying²,Yu Jun-Lin¹,Yang Ling-Ling²^ORCID,Li Guo-Bo¹^ORCID

Affiliation:

1. Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Department of Medicinal Chemistry, West China School of Pharmacy, Sichuan University, Chengdu 610041, China

2. College of Food and Bioengineering, Xihua University, Chengdu 610039, China

Funder

Sichuan University

National Key Research and Development Program of China

Science and Technology Department of Sichuan Province

National Natural Science Foundation of China

State Key Laboratory of Esophageal Cancer Prevention and Treatment

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c01514

Reference44 articles.

1. Breaking the chains: deubiquitylating enzyme specificity begets function

2. Mechanisms of regulation and diversification of deubiquitylating enzyme function

3. Mechanisms of Deubiquitinase Specificity and Regulation

4. A Genomic and Functional Inventory of Deubiquitinating Enzymes

5. Breaking the chains: structure and function of the deubiquitinases

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