Discovery of Novel <i>Neo</i>-Clerodane Derivatives as Potent Dual-Functional Antiosteoporosis Agents through Targeting Peroxisome Proliferator-Activated Receptor-γ-Reference-Cited by-同舟云学术

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Discovery of Novel Neo-Clerodane Derivatives as Potent Dual-Functional Antiosteoporosis Agents through Targeting Peroxisome Proliferator-Activated Receptor-γ

Published:2024-08-26 Issue:17 Volume:67 Page:15738-15755
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Peng Xing¹,Zhang Zhikang¹,Zhang Yuting¹,Zhou Huihao¹^ORCID,Li Wenqi²,Dai Minxian²,Shang Jinsai²^ORCID,Xu Jun¹^ORCID,Gu Qiong¹^ORCID

Affiliation:

1. Research Center for Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, People’s Republic of China

2. School of Basic Medical Sciences, Guangzhou Laboratory, Guangzhou Medical University, Guangzhou 511436, People’s Republic of China

Funder

Guangzhou Municipal Science and Technology Project

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c01377

Reference37 articles.

1. Osteoporosis: now and the future

2. The Prevalence of Osteoporosis in China, a Nationwide, Multicenter DXA Survey

3. Osteoclast differentiation and activation

4. Advances in the Regulation of Osteoclasts and Osteoclast Functions

5. Osteoblast as a target of anti-osteoporotic treatment

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