Expanding Structure–Activity Relationships of Human Urotensin II Peptide Analogues: A Proposed Key Role of the N-Terminal Region for Novel Urotensin II Receptor Modulators-Reference-Cited by-同舟云学术

Expanding Structure–Activity Relationships of Human Urotensin II Peptide Analogues: A Proposed Key Role of the N-Terminal Region for Novel Urotensin II Receptor Modulators

Published:2024-08-03 Issue:16 Volume:67 Page:13879-13890
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Merlino Francesco¹²^ORCID,Secondo Agnese³,Mitidieri Emma¹,Sorrentino Raffaella¹,Bellavita Rosa¹^ORCID,Grasso Nicola¹^ORCID,Chatenet David⁴,Pannaccione Anna³,Grieco Paolo¹²^ORCID,d’Emmanuele di Villa Bianca Roberta¹,Carotenuto Alfonso¹²^ORCID

Affiliation:

1. Department of Pharmacy, School of Medicine and Surgery, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy

2. Centro Interuniversitario di Ricerca sui Peptidi Bioattivi “Carlo Pedone” (CIRPeB), University of Naples Federico II, via Mezzocannone 16, 80134 Naples, Italy

3. Division of Pharmacology, Department of Neuroscience, Reproductive and Dentistry Sciences, School of Medicine and Surgery, University of Naples Federico II, Via Pansini 5, 80131 Naples, Italy

4. Institut National de la Recherche Scientifique (INRS), Centre Armand-Frappier Santé Biotechnologie, Université du Québec, H7 V 1B7 Québec, Canada

Funder

Regione Campania

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c00688

Reference57 articles.

1. Towards Targeting the Urotensinergic System: Overview and Challenges

2. International Union of Basic and Clinical Pharmacology. XCII. Urotensin II, Urotensin II–Related Peptide, and Their Receptor: From Structure to Function

3. Update on the urotensinergic system: new trends in receptor localization, activation, and drug design

4. Urotensin II: a somatostatin-like peptide in the caudal neurosecretory system of fishes.

5. Cloning of the cDNA encoding the urotensin II precursor in frog and human reveals intense expression of the urotensin II gene in motoneurons of the spinal cord