Peptidic Boronic Acid <i>Plasmodium falciparum</i> SUB1 Inhibitors with Improved Selectivity over Human Proteasome-Reference-Cited by-同舟云学术

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Peptidic Boronic Acid Plasmodium falciparum SUB1 Inhibitors with Improved Selectivity over Human Proteasome

Published:2024-07-25 Issue:15 Volume:67 Page:13033-13055
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Withers-Martinez Chrislaine¹,Lidumniece Elina²,Hackett Fiona¹,Collins Christine R.¹,Taha Zahie¹,Blackman Michael J.¹³^ORCID,Jirgensons Aigars²^ORCID

Affiliation:

1. Malaria Biochemistry Laboratory, The Francis Crick Institute, London NW1 1AT, U.K.

2. Latvian Institute of Organic Synthesis, Riga LV-1006, Latvia

3. Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London WC1E 7HT, U.K.

Funder

Medical Research Council

Wellcome Trust

Latvijas Zinatnes Padome

Cancer Research UK

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c01005

Reference48 articles.

1. WHO, World Malaria Report 2018 World Health Organization: Geneva, 2016 http://www.who.int/malaria/publications/world-malaria-report-2018/report/en. (Accessed 25.04.2024).

2. Malaria medicines: a glass half full?

3. Pyrimethamine–sulfadoxine resistance in Plasmodium falciparum: what next?

4. Resistance to Antifolates in Plasmodium Falciparum, the Causative Agent of Tropical Malaria

5. Evidence of Artemisinin-Resistant Malaria in Africa

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