Discovery of MT-1207: A Novel, Potent Multitarget Inhibitor as a Promising Clinical Candidate for the Treatment of Hypertension-Reference-Cited by-同舟云学术

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Discovery of MT-1207: A Novel, Potent Multitarget Inhibitor as a Promising Clinical Candidate for the Treatment of Hypertension

Published:2024-07-05 Issue: Volume: Page:
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wang Peng¹,Zhu Huajian¹,Tian Jia-Sheng²,Zhu Wenjian¹,Xu Shengtao¹,Yao Hong¹^ORCID,Liu Jie¹,Zhu Zheying³,Miao Chao-Yu²,Xu Jinyi¹^ORCID

Affiliation:

1. State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China

2. Department of Pharmacology, Second Military Medical University/Naval Medical University, Shanghai 200433, China

3. Division of Molecular Therapeutics & Formulation, School of Pharmacy, The University of Nottingham, Nottingham NG7 2RD, U.K.

Funder

China Pharmaceutical University

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c00626

Reference23 articles.

1. Evolution of a New Class of Antihypertensive Drugs

2. Emerging Drug Classes and Their Potential Use in Hypertension

3. Treatment of hypertension with an angiotensin II—receptor antagonist compared with an angiotensin-converting enzyme inhibitor: A review of clinical studies of telmisartan and enalapril

4. Cough and Angioneurotic Edema Associated with Angiotensin-Converting Enzyme Inhibitor Therapy

5. Atypical reactions associated with use of angiotensin-converting enzyme inhibitors and apheresis

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