Structure–Activity Relationships of Natural and Semisynthetic Plecomacrolides Suggest Distinct Pathways for HIV-1 Immune Evasion and Vacuolar ATPase-Dependent Lysosomal Acidification-Reference-Cited by-同舟云学术

Structure–Activity Relationships of Natural and Semisynthetic Plecomacrolides Suggest Distinct Pathways for HIV-1 Immune Evasion and Vacuolar ATPase-Dependent Lysosomal Acidification

Published:2024-03-07 Issue:6 Volume:67 Page:4483-4495
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

McCauley Morgan¹,Huston Matthew²,Condren Alanna R.¹,Pereira Filipa¹,Cline Joel²,Yaple-Maresh Marianne²,Painter Mark M.³,Zimmerman Gretchen E.²,Robertson Andrew W.¹⁴,Carney Nolan⁵,Goodall Christopher²,Terry Valeri²,Müller Rolf⁶,Sherman David H.⁷¹⁸⁵^ORCID,Collins Kathleen L.³²⁷

Affiliation:

1. University of Michigan, Life Sciences Institute, Ann Arbor, Michigan 48109, United States

2. University of Michigan, Department of Internal Medicine, Ann Arbor, Michigan 48109, United States

3. University of Michigan, Graduate Program in Immunology, Ann Arbor, Michigan 48109, United States

4. University of Michigan Natural Products Discovery Core, Life Sciences Institute, Ann Arbor, Michigan 48109, United States

5. University of Michigan, Department of Chemistry, Ann Arbor, Michigan 48109, United States

6. Helmholtz Institute for Pharmaceutical Research Saarland, Saarbrücken 66123, Germany

7. University of Michigan, Department of Microbiology & Immunology, Ann Arbor, Michigan 48109, United States

8. University of Michigan, Department of Medicinal Chemistry, Ann Arbor, Michigan 48109, United States

Funder

University of Michigan

National Institutes of Health

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c01574

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