Development of a Selective Peptide κ-Opioid Receptor Antagonist by Late-Stage Functionalization with Cysteine Staples-Reference-Cited by-同舟云学术

Development of a Selective Peptide κ-Opioid Receptor Antagonist by Late-Stage Functionalization with Cysteine Staples

Published:2023-08-26 Issue:17 Volume:66 Page:11843-11854
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Muratspahić Edin¹,White Andrew M.²,Ciotu Cosmin I.³,Hochrainer Nadine⁴,Tomašević Nataša¹,Koehbach Johannes²^ORCID,Lewis Richard J.⁵^ORCID,Spetea Mariana⁴^ORCID,Fischer Michael J. M.³^ORCID,Craik David J.²^ORCID,Gruber Christian W.¹^ORCID

Affiliation:

1. Center for Physiology and Pharmacology, Institute of Pharmacology, Medical University of Vienna, 1090 Vienna, Austria

2. Institute for Molecular Bioscience, Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, 4072 Brisbane, Queensland, Australia

3. Center for Physiology and Pharmacology, Institute of Physiology, Medical University of Vienna, 1090 Vienna, Austria

4. Department of Pharmaceutical Chemistry, Institute of Pharmacy and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria

5. Institute for Molecular Bioscience, The University of Queensland, 4072 Brisbane, Queensland, Australia

Funder

Universit?t Innsbruck

Austrian Science Fund

National Health and Medical Research Council

Australian Research Council

Bundesministerium f?r Bildung, Wissenschaft und Forschung

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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