Discovery, Synthesis, and Evaluation of Novel Dual Inhibitors of a Vascular Endothelial Growth Factor Receptor and Poly(ADP-Ribose) Polymerase for BRCA Wild-Type Breast Cancer Therapy

Author:

Li Yang1,Liu Yun1,Zhang Dan1,Chen Juncheng1,Yang Gaoxia1,Tang Pan1,Yang Chengcan1,Liu Jie1,Zhang Jifa12ORCID,Ouyang Liang12ORCID

Affiliation:

1. Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy and Joint Research Institution of Altitude Health and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, China

2. Frontiers Medical Center, Tianfu Jincheng Laboratory, Chengdu, 610212, China

Funder

Sichuan University

West China Hospital, Sichuan University

National Natural Science Foundation of China

Sichuan Province Science and Technology Support Program

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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