Development and <i>In Vivo</i> Evaluation of Small-Molecule Ligands for Positron Emission Tomography of Immune Checkpoint Modulation Targeting Programmed Cell Death 1 Ligand 1-Reference-Cited by-同舟云学术

Development and In Vivo Evaluation of Small-Molecule Ligands for Positron Emission Tomography of Immune Checkpoint Modulation Targeting Programmed Cell Death 1 Ligand 1

Published:2024-03-05 Issue:5 Volume:67 Page:4036-4062
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bamminger Karsten¹²,Pichler Verena¹³^ORCID,Vraka Chrysoula²,Limberger Tanja¹⁴,Moneva Boryana²,Pallitsch Katharina⁵^ORCID,Lieder Barbara⁶⁷^ORCID,Zacher Anna Sophia²,Ponti Stefanie²,Benčurová Katarína²,Yang Jiaye⁴,Högler Sandra⁸,Kodajova Petra⁸,Kenner Lukas¹⁴⁸,Hacker Marcus²,Wadsak Wolfgang¹²^ORCID

Affiliation:

1. CBmed GmbH - Center for Biomarker Research in Medicine, 8010 Graz, Austria

2. Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, 1090 Vienna, Austria

3. Department of Pharmaceutical Sciences, Division of Pharmaceutical Chemistry, University of Vienna, 1090 Vienna, Austria

4. Institute of Clinical Pathology, Medical University of Vienna, 1090 Vienna, Austria

5. Institute of Organic Chemistry, University of Vienna, 1090 Vienna, Austria

6. Institute of Physiological Chemistry, University of Vienna, 1090 Vienna, Austria

7. Institute of Clinical Nutrition, University of Hohenheim, 70599 Stuttgart, Germany

8. Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, 1210 Vienna, Austria

Funder

?sterreichische Forschungsf?rderungsgesellschaft

Steirische Wirtschaftsf?rderungsgesellschaft

Amt der Steierm?rkischen Landesregierung

Veterin?rmedizinische Universit?t Wien

Medizinische Universit?t Wien

Bundesministerium f?r Klimaschutz, Umwelt, Energie, Mobilit?t, Innovation und Technologie

Government of Austria

ITM Munich

SOFIE Biosciences

Ministry for Labour and Economy

Vienna, Federal State

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c02342

Reference50 articles.

1. Efficacy of PD-1/PD-L1 blockade monotherapy in clinical trials

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3. [89Zr]-Atezolizumab-PET Imaging Reveals Longitudinal Alterations in PDL1 during Therapy in TNBC Preclinical Models

4. PD-L1 PET/CT imaging with radiolabeled durvalumab in patients with advanced stage non-small cell lung cancer.

5. First-in-human study of 89Zr-pembrolizumab PET/CT in patients with advanced stage non-small-cell lung cancer

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