Discovery of a Potent Nicotinamide Phosphoribosyltransferase Activator for Improving Aging-associated Dysfunctions-Reference-Cited by-同舟云学术

Discovery of a Potent Nicotinamide Phosphoribosyltransferase Activator for Improving Aging-associated Dysfunctions

Published:2024-02-17 Issue:5 Volume:67 Page:4120-4130
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Yang Sicheng¹,Sun Donghuan¹,Wu Ying¹²,Chen Shuqiang¹,Guo Yuan³^ORCID,Li Jian⁴^ORCID,Dong Guoqiang¹^ORCID,Sheng Chunquan¹^ORCID

Affiliation:

1. The Center for Basic Research and Innovation of Medicine and Pharmacy (MOE), School of Pharmacy, Second Military Medical University (Naval Medical University), 325 Guohe Road, Shanghai 200433, China

2. Department of Clinical Pharmacy, 920th Hospital of Joint Logistics Support Force, Kunming 650032, China

3. College of Chemistry and Materials Science, Northwest University, Xi’an 710127, China

4. School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c02370

Reference41 articles.

1. NAD metabolism: Implications in aging and longevity

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3. NAD + in Aging: Molecular Mechanisms and Translational Implications

4. Emerging potential benefits of modulating NAD+ metabolism in cardiovascular disease

5. The senescent bystander effect is caused by ROS-activated NF-κB signalling

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