Design, Synthesis, and Biological Evaluation of Novel Hybrids Containing Dihydrochalcone as Tyrosinase Inhibitors to Treat Skin Hyperpigmentation-Reference-Cited by-同舟云学术

Design, Synthesis, and Biological Evaluation of Novel Hybrids Containing Dihydrochalcone as Tyrosinase Inhibitors to Treat Skin Hyperpigmentation

Published:2023-03-20 Issue:7 Volume:66 Page:5099-5117
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Xue Songtao¹,Li Zhiwei²,Ze Xiaotong¹,Wu Xiuyuan¹,He Chen¹,Shuai Wen¹,Marlow Maria²^ORCID,Chen Jian³,Scurr David²^ORCID,Zhu Zheying²,Xu Jinyi¹^ORCID,Xu Shengtao¹³^ORCID

Affiliation:

1. School of Pharmacy, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, P. R. China

2. School of Pharmacy, The University of Nottingham, University Park Campus, Nottingham NG7 2RD, UK

3. Department of Hepatobiliary Surgery, The First People’s Hospital of Kunshan, Suzhou 215300, P. R. China

Funder

China Pharmaceutical University

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c00012

Reference64 articles.

1. Pigmentation disorders: hyperpigmentation and hypopigmentation

2. Physiological factors that regulate skin pigmentation

3. Alterations in the epidermal-dermal melanin axis and factor XIIIa melanophages in senile lentigo and ageing skin

4. Melanin Biosynthesis Inhibitors from the Bark of Machilus thunbergii

5. Role of Tyrosinase as the Determinant of Pigmentation in Cultured Human Melanocytes

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