Discovery of Novel Pyridazine-Tethered Sulfonamides as Carbonic Anhydrase II Inhibitors for the Management of Glaucoma-Reference-Cited by-同舟云学术

Discovery of Novel Pyridazine-Tethered Sulfonamides as Carbonic Anhydrase II Inhibitors for the Management of Glaucoma

Published:2024-01-11 Issue:2 Volume:67 Page:1611-1623
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Tawfik Haytham O.¹^ORCID,Saleh Mohamed M.¹^ORCID,Ammara Andrea²^ORCID,Khaleel Eman F.³,Badi Rehab³,Khater Yomna T. T.⁴,Rasheed Rabab A.⁵^ORCID,Attia Ahmed A.⁶,Hefny Salma M.¹^ORCID,Elkaeed Eslam B.⁷⁸,Nocentini Alessio²^ORCID,Supuran Claudiu T.²^ORCID,Eldehna Wagdy M.⁹^ORCID,Shaldam Moataz A.⁹^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Tanta University, Tanta 31527, Egypt

2. Department of NEUROFARBA, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Polo Scientifico, Via U. Schiff 6, Sesto Fiorentino 50019, Firenze, Italy

3. Department of Medical Physiology, College of Medicine, King Khalid University, Abha 61421, Saudi Arabia

4. Medical Experimental Research Center, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt

5. Department of Medical Histology and Cell Biology, Faculty of Medicine, King Salman International University, South Sinai 46511, Egypt

6. Mansoura Ophthalmic Center, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt

7. Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo 11884, Egypt

8. Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh 13713, Saudi Arabia

9. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, P.O. Box 33516, Kafrelsheikh 33516, Egypt

Funder

Deanship of Scientific Research, King Khalid University

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c02279

Reference54 articles.

1. The number of people with glaucoma worldwide in 2010 and 2020

2. Discovery of Potent Dual-Tailed Benzenesulfonamide Inhibitors of Human Carbonic Anhydrases Implicated in Glaucoma and in Vivo Profiling of Their Intraocular Pressure-Lowering Action

3. The Application of Nitric Oxide for Ocular Hypertension Treatment

4. Novel therapies for glaucoma: a patent review (2013-2019)

5. Novel 3-(6-methylpyridin-2-yl)coumarin-based chalcones as selective inhibitors of cancer-related carbonic anhydrases IX and XII endowed with anti-proliferative activity

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