Rebamipide and Derivatives are Potent, Selective Inhibitors of Histidine Phosphatase Activity of the Suppressor of T Cell Receptor Signaling Proteins-Reference-Cited by-同舟云学术

Rebamipide and Derivatives are Potent, Selective Inhibitors of Histidine Phosphatase Activity of the Suppressor of T Cell Receptor Signaling Proteins

Published:2024-01-22 Issue: Volume: Page:
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Aziz Faisal¹,Reddy Kanamata¹,Fernandez Vega Virneliz²,Dey Raja¹,Hicks Katherine A.³^ORCID,Rao Sumitha²,Jordan Luis Ortiz²,Smith Emery²,Shumate Justin²,Scampavia Louis²,Carpino Nicholas⁴,Spicer Timothy P.²,French Jarrod B.¹^ORCID

Affiliation:

1. The Hormel Institute, University of Minnesota, Austin, Minnesota 55912, United States

2. Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute, Jupiter, Florida 33458, United States

3. Department of Chemistry, State University of New York at Cortland, Cortland, New York 13045, United States

4. Department of Microbiology and Immunology, Stony Brook University, Stony Brook, New York 11790, United States

Funder

Division of Molecular and Cellular Biosciences

Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c01763

Reference48 articles.

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4. Insights into the suppressor of T-cell receptor (TCR) signaling-1 (Sts-1)-mediated regulation of TCR signaling through the use of novel substrate-trapping Sts-1 phosphatase variants

5. TULA proteins as signaling regulators