6-Substituted Triazolyl Benzoxaboroles as Selective Carbonic Anhydrase Inhibitors: <i>In Silico</i> Design, Synthesis, and X-ray Crystallography-Reference-Cited by-同舟云学术

6-Substituted Triazolyl Benzoxaboroles as Selective Carbonic Anhydrase Inhibitors: In Silico Design, Synthesis, and X-ray Crystallography

Published:2023-06-07 Issue:12 Volume:66 Page:8118-8129
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Nocentini Alessio¹²^ORCID,Bonardi Alessandro¹²,Bazzicalupi Carla³^ORCID,Alterio Vincenzo⁴,Esposito Davide⁴,Monti Simona Maria⁴,Smietana Michael⁵^ORCID,De Simone Giuseppina⁴^ORCID,Supuran Claudiu T.¹^ORCID,Gratteri Paola²^ORCID,Winum Jean-Yves⁵^ORCID

Affiliation:

1. NEUROFARBA Department, Pharmaceutical and Nutraceutical Section, University of Florence, Via U. Schiff 6, 50019 Sesto Fiorentino, Firenze, Italy

2. NEUROFARBA Department, Pharmaceutical and Nutraceutical Section, Laboratory of Molecular Modeling Cheminformatics & QSAR, University of Florence, Via U. Schiff 6, 50019 Sesto Fiorentino, Firenze, Italy

3. Department of Chemistry “Ugo Schiff”, University of Florence, Via della Lastruccia 3-13, 50019 Sesto Fiorentino, Italy

4. Institute of Biostructures and Bioimaging, Consiglio Nazionale delle Ricerche, Via Pietro Castellino, 111, 80131 Naples, Italy

5. IBMM, Univ Montpellier, CNRS, ENSCM, 1919 route de Mende, 34293 Montpellier, cedex 5, France

Funder

Consiglio Nazionale delle Ricerche

Centro de Investigaci?n y de Estudios Avanzados del Instituto Polit?cnico Nacional

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c00433

Reference49 articles.

1. The Boron Advantage: The Evolution and Diversification of Boron’s Applications in Medicinal Chemistry

2. Boron-Based Drug Design

3. Boron Chemicals in Drug Discovery and Development: Synthesis and Medicinal Perspective

4. Recent developments in the medicinal chemistry of single boron atom-containing compounds

5. Boron in drug design: Recent advances in the development of new therapeutic agents

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