Discovery of Selective P2Y<sub>6</sub>R Antagonists with High Affinity and <i>In Vivo</i> Efficacy for Inflammatory Disease Therapy-Reference-Cited by-同舟云学术

Discovery of Selective P2Y₆R Antagonists with High Affinity and In Vivo Efficacy for Inflammatory Disease Therapy

Published:2023-04-20 Issue:9 Volume:66 Page:6315-6332
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhu Yifan¹,Zhou Mengze²,Cheng Xiangyu²,Wang Hui¹,Li Yehong²,Guo Yueyue¹,Wang Yaxuan¹,Tian Sheng¹³,Mao Tianqi¹,Zhang Zhoudong¹,Li Duxin¹^ORCID,Hu Qinghua²^ORCID,Li Huanqiu¹^ORCID

Affiliation:

1. College of Pharmaceutical Sciences, Soochow University, Suzhou 215006, PR China

2. School of Pharmacy, China Pharmaceutical University, Nanjing 211198, PR China

3. Jiangsu Province Engineering Research Center of Precision Diagnostics and Therapeutics Development, Soochow University, Suzhou 215006, PR China

Funder

Suzhou Municipal Science and Technology Bureau

Qinglan Project of Jiangsu Province of China

Natural Science Foundation of Jiangsu Province

Priority Academic Program Development of Jiangsu Higher Education Institutions

Natural science fund for colleges and universities in Jiangsu Province

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c00210

Reference51 articles.

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5. The role of P2Y receptors in regulating immunity and metabolism

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