Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity

Author:

Dichiara Maria1ORCID,Ambrosio Francesca Alessandra2ORCID,Lee Sang Min3,Ruiz-Cantero M. Carmen4ORCID,Lombino Jessica1,Coricello Adriana5ORCID,Costa Giosuè56ORCID,Shah Dhara3,Costanzo Giuliana1,Pasquinucci Lorella1ORCID,Son Kyung No7,Cosentino Giuseppe1,González-Cano Rafael4,Marrazzo Agostino1ORCID,Aakalu Vinay Kumar7,Cobos Enrique J.4,Alcaro Stefano56ORCID,Amata Emanuele1ORCID

Affiliation:

1. Dipartimento di Scienze del Farmaco e della Salute, Università degli Studi di Catania, Viale Andrea Doria 6, 95125 Catania, Italy

2. Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi “Magna Græcia” di Catanzaro, Campus “S. Venuta”, Viale Europa, 88100 Catanzaro, Italy

3. Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, 1905 W Taylor St, Chicago, Illinois 60612, United States

4. Departamento de Farmacología e Instituto de Neurociencias, Facultad de Medicina, Universitad de Granada e Instituto de Investigación Biosanitaria de Granada ibs.GRANADA, Avenida de la Investigación, 18016 Granada, Spain

5. Dipartimento di Scienze della Salute, Università “Magna Græcia” di Catanzaro, Campus “S. Venuta”, 88100 Catanzaro, Italy

6. Net4Science Academic Spin-Off, Università “Magna Græcia” di Catanzaro, Campus “S. Venuta”, 88100 Catanzaro, Italy

7. Department of Ophthalmology and Visual Sciences, University of Michigan, 1000 Wall Street, Ann Arbor, Michigan 48105, United States

Funder

National Institute of Neurological Disorders and Stroke

National Eye Institute

Research to Prevent Blindness

Junta de Andalucía

Agencia Estatal de Investigación

Ministero dell’Istruzione, dell’Università e della Ricerca

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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