Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases-Reference-Cited by-同舟云学术

Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases

Published:2024-01-12 Issue:2 Volume:67 Page:1460-1480
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wang Lushun¹^ORCID,Bohmer Monica J.²^ORCID,Wang Jinhua³⁴,Nardella Flore²,Calla Jaeson⁵,Laureano De Souza Mariana⁵^ORCID,Schindler Kyra A.⁶,Montejo Lukas²,Mittal Nimisha⁵,Rocamora Frances⁵,Treat Mayland⁷,Charlton Jordan T.⁸,Tumwebaze Patrick K.⁹,Rosenthal Philip J.¹⁰,Cooper Roland A.⁸,Chakrabarti Ratna¹¹,Winzeler Elizabeth A.⁵^ORCID,Chakrabarti Debopam²^ORCID,Gray Nathanael S.¹^ORCID

Affiliation:

1. Department of Chemical and Systems Biology, ChEM-H, Stanford Cancer Institute, School of Medicine, Stanford University, Stanford, California 94305, United States

2. Division of Molecular Microbiology, Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida 32826, United States

3. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02215, United States

4. Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, United States

5. Department of Pediatrics, School of Medicine, University California, San Diego, La Jolla, California 92093, United States

6. Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, New York 10032, United States

7. School of Public Health, University of California, Berkeley California 94704, United States

8. Department of Natural Sciences and Mathematics, Dominican University of California, San Rafael, California 94901, United States

9. Infectious Disease Research Collaboration, Kampala, Uganda

10. Department of Medicine, University of California, San Francisco, California 94110, United States

11. Division of Cancer Research, Burnett School of Biomedical Sciences, University of Central Florida, Orlando, Florida 32826, United States

Funder

National Institute of Allergy and Infectious Diseases

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c02046

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4. Kinase inhibitors: the road ahead