Preferred Conformation-Guided Discovery of Potent and Orally Active HIF Prolyl Hydroxylase 2 Inhibitors for the Treatment of Anemia-Reference-Cited by-同舟云学术

Preferred Conformation-Guided Discovery of Potent and Orally Active HIF Prolyl Hydroxylase 2 Inhibitors for the Treatment of Anemia

Published:2023-06-27 Issue:13 Volume:66 Page:8545-8563
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wu Yue¹²^ORCID,Zhang Linjian¹²,Sun Zhuoli¹³,Qiu Xusheng⁴,Chen Yafen¹³,Su Kaijun¹²,Yang Le¹²,Du Zhongqiu⁴,Dong Ying¹²,Yang Fulai¹²^ORCID,Li Xiang¹³^ORCID,Zhang Xiaojin¹²^ORCID

Affiliation:

1. State Key Laboratory of Natural Medicines, and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China

2. Department of Chemistry, China Pharmaceutical University, Nanjing 211198, China

3. Department of Pharmaceutical Engineering, China Pharmaceutical University, Nanjing 211198, China

4. Department of Orthopedics, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China

Funder

China Pharmaceutical University

Natural Science Foundation of Jiangsu Province

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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