Discovery of a First-in-Class GPR183 Antagonist for the Potential Treatment of Rheumatoid Arthritis
Author:
Funder
Immunophage Biotech Co., Ltd
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c01364
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1. EBI2 in splenic and local immune responses and in autoimmunity
2. Control of TH17 cells occurs in the small intestine
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4. The EBI2-oxysterol axis promotes the development of intestinal lymphoid structures and colitis
5. EBI2 Is Highly Expressed in Multiple Sclerosis Lesions and Promotes Early CNS Migration of Encephalitogenic CD4 T Cells
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