Structure-Based Discovery of High-Affinity Small Molecule Ligands and Development of Tool Probes to Study the Role of Chitinase-3-Like Protein 1-Reference-Cited by-同舟云学术

Structure-Based Discovery of High-Affinity Small Molecule Ligands and Development of Tool Probes to Study the Role of Chitinase-3-Like Protein 1

Published:2024-03-01 Issue:5 Volume:67 Page:3959-3985
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Czestkowski Wojciech¹,Krzemiński Łukasz¹,Piotrowicz Michał C.¹^ORCID,Mazur Marzena¹,Pluta Elżbieta¹,Andryianau Gleb¹,Koralewski Robert¹,Matyszewski Krzysztof¹,Olejniczak Sylwia¹,Kowalski Michał¹,Lisiecka Katarzyna¹,Kozieł Rafał¹,Piwowar Katarzyna¹,Papiernik Diana¹,Nowotny Marcin²^ORCID,Napiórkowska-Gromadzka Agnieszka²,Nowak Elżbieta²,Niedziałek Dorota¹,Wieczorek Grzegorz¹,Siwińska Anna¹,Rejczak Tomasz¹,Jędrzejczak Karol¹,Mulewski Krzysztof¹,Olczak Jacek¹^ORCID,Zasłona Zbigniew¹,Gołębiowski Adam¹^ORCID,Drzewicka Katarzyna¹,Bartoszewicz Agnieszka¹^ORCID

Affiliation:

1. Molecure S.A., Żwirki I Wigury 101, Warsaw 02-089, Poland

2. Laboratory of Protein Structure, International Institute of Molecular and Cell Biology in Warsaw, Ks. Trojdena 4, Warsaw 02-109, Poland

Funder

European Regional Development Fund

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c02255

Reference76 articles.

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2. In vitro expression of a 38,000 dalton heparin-binding glycoprotein by morphologically differentiated smooth muscle cells

3. Isolation and characterization of a novel 39 kilodaton whey protein from bovine mammary secretions collected during the nonlactating period

4. Human synovial cells secrete a 39 kDa protein similar to a bovine mammary protein expressed during the non-lactating period

5. Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family.

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