Allosteric Activation of α7 Nicotinic Acetylcholine Receptors by Novel 2-Arylamino-thiazole-5-carboxylic Acid Amide Derivatives for the Improvement of Cognitive Deficits in Mice-Reference-Cited by-同舟云学术

Allosteric Activation of α7 Nicotinic Acetylcholine Receptors by Novel 2-Arylamino-thiazole-5-carboxylic Acid Amide Derivatives for the Improvement of Cognitive Deficits in Mice

Published:2024-02-23 Issue:8 Volume:67 Page:6344-6364
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Yang Chenxia¹,Meng Ying²,Wang Xintong²,Li Xin²,Yu Tong²,Liao Weiming²,Xie Wenjun²,Jiang Qianchen²,Wang Han²,Shi Cheng²,Jiao Wenxuan²,Bian Xiling²,Hu Fang¹,Wang Xiaowei²,Liu Yani¹³^ORCID,Zhang Liangren²^ORCID,Wang KeWei¹³^ORCID,Sun Qi²^ORCID

Affiliation:

1. Department of Pharmacology, School of Pharmacy, Qingdao University Medical College, #1 Ningde Road, Qingdao 266073, China

2. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China

3. Institute of Innovative Drugs, 38 Dengzhou Road, Qingdao University, Qingdao 266021, China

Funder

the funds of National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c02323

Reference43 articles.

1. α7-Nicotinic Acetylcholine Receptor Agonists for Cognitive Enhancement in Schizophrenia

2. Therapeutic Potential of α7 Nicotinic Acetylcholine Receptors

3. The current agonists and positive allosteric modulators of α 7 nAChR for CNS indications in clinical trials

4. Nicotinic acetylcholine receptor-mediated calcium signaling in the nervous system

5. α7 nicotinic acetylcholine receptors as therapeutic targets in schizophrenia: Update on animal and clinical studies and strategies for the future

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