Small Molecule Ligands of the BET-like Bromodomain, SmBRD3, Affect Schistosoma mansoni Survival, Oviposition, and Development

Author:

Schiedel Matthias1ORCID,McArdle Darius J. B.1,Padalino Gilda2,Chan Anthony K. N.1ORCID,Forde-Thomas Josephine2,McDonough Michael1,Whiteland Helen2,Beckmann Manfred2,Cookson Rosa3,Hoffmann Karl F.2ORCID,Conway Stuart J.14ORCID

Affiliation:

1. Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, U.K.

2. The Department of Life Sciences (DLS), Aberystwyth University, Wales SY23 3DA, U.K.

3. GlaxoSmithKline R&D, Stevenage, Hertfordshire SG1 2NY, U.K.

4. Department of Chemistry & Biochemistry, University of California Los Angeles, 607 Charles E. Young Drive East, P.O. Box 951569, Los Angeles, California 90095-1569, United States

Funder

Life Sciences Research Network Wales

University of California, Los Angeles

Deutsche Forschungsgemeinschaft

GlaxoSmithKline

Horizon 2020 Framework Programme

St. Hugh's College, University of Oxford

Biotechnology and Biological Sciences Research Council

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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