Discovery of an Anti-TNF-α 9-mer Peptide from a T7 Phage Display Library for the Treatment of Inflammatory Bowel Disease-Reference-Cited by-同舟云学术

Discovery of an Anti-TNF-α 9-mer Peptide from a T7 Phage Display Library for the Treatment of Inflammatory Bowel Disease

Published:2023-05-16 Issue:10 Volume:66 Page:6981-6993
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wang Helin¹²,Wang Junjie¹,Zhao Xin¹,Ye Ruiwei³,Sun Li²,Wang Jiaojiao²,Li Linxue³,Liang Hong²^ORCID,Wang Sheng¹,Lu Yiming¹³^ORCID

Affiliation:

1. Department of Critical Care Medicine, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai 200072, China

2. State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Science, Guangxi Normal University, Guilin 541004, China

3. School of Medicine, Shanghai University, Shanghai 200444, China

Funder

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Science and Technology Innovation Plan Of Shanghai Science and Technology Commission

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c00436

Reference25 articles.

1. Signalling pathways of the TNF superfamily: a double-edged sword

2. Cytokines in inflammatory bowel disease

3. TNF hampers intestinal tissue repair in colitis by restricting IL-22 bioavailability

4. Tracking TNF and anti-TNF agents in inflamed gut tissue

5. Development of novel oridonin analogs as specifically targeted NLRP3 inflammasome inhibitors for the treatment of dextran sulfate sodium-induced colitis

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