Design of Selective PARP-1 Inhibitors and Antitumor Studies-Reference-Cited by-同舟云学术

Design of Selective PARP-1 Inhibitors and Antitumor Studies

Published:2024-05-22 Issue:11 Volume:67 Page:8877-8901
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhang Yiting¹^ORCID,Li Xiangqian¹²,Liu Fang¹,Bai Xiaoyi¹,Liu Xiaochun³,Sun Hao¹,Gao Chenxia¹,Lin Yuxi¹,Xing Pan¹,Zhu Jiqiang⁴,Liu Ruihua¹,Wang Zemin¹,Dai Jiajia⁵,Shi Dayong¹²⁴^ORCID

Affiliation:

1. State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China

2. Laboratory of Marine Drugs and Biological Products, Pilot National Laboratory for Marine Science and Technology, Qingdao 266237, China

3. Marine Biomedical Research Institute of Qingdao, Qingdao 266071, China

4. Shandong Linghai Biotechnology Co.Ltd., Jinan 250299, Shandong, P. R. China

5. Key Laboratory of Marine Ecology and Environmental Sciences, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, Shandong, China

Funder

National Key Research and Development Program of China

Natural Science Foundation of Shandong Province

Chinese Academy of Sciences

Shandong Province

Qingdao Emerging Industry Cultivation Project

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c02460

Reference44 articles.

1. PARP-inhibitor potpourri: A comparative review of class safety, efficacy, and cost

2. NAD+ analog reveals PARP-1 substrate-blocking mechanism and allosteric communication from catalytic center to DNA-binding domains

3. Repair of Double-Strand Breaks by End Joining

4. Homology-Directed Repair and the Role of BRCA1, BRCA2, and Related Proteins in Genome Integrity and Cancer

5. Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells