Targeting the CSF-1/CSF-1R Axis: Exploring the Potential of CSF1R Inhibitors in Neurodegenerative Diseases-Reference-Cited by-同舟云学术

Targeting the CSF-1/CSF-1R Axis: Exploring the Potential of CSF1R Inhibitors in Neurodegenerative Diseases

Published:2024-03-26 Issue:7 Volume:67 Page:5699-5720
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Baek Jihyun¹,Jun Joonhong¹,Kim Hyejin¹,Bae Hyunah¹,Park Haebeen¹,Cho Hyunwook¹,Han Songhee²,Shin Ho Chul²,Hah Jung-Mi¹^ORCID

Affiliation:

1. Department of Pharmacy, Institute of Pharmaceutical Science and Technology, College of Pharmacy, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan, Kyeonggi-do 15588, Republic of Korea

2. Research Center, Whan In Pharmaceutical Co., Ltd., 11, Beobwon-ro 6-gil, Songpa-gu, Seoul 05855, Korea

Funder

National Research Foundation of Korea

Whan In Pharm. Co., Ltd.

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c02366

Reference29 articles.

1. The Colony Stimulating Factor-1 Receptor (CSF-1R)-Mediated Regulation of Microglia/Macrophages as a Target for Neurological Disorders (Glioma, Stroke)

2. Targeting CSF-1R represents an effective strategy in modulating inflammatory diseases

3. Mutational analysis of class III receptor tyrosine kinases (C-KIT, C-FMS, FLT3) in idiopathic myelofibrosis

4. Colony-stimulating factor 1 receptor signaling in the central nervous system and the potential of its pharmacological inhibitors to halt the progression of neurological disorders

5. Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?

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