Rational Design of Bioorthogonally Activatable PROTAC for Tumor-Targeted Protein Degradation-Reference-Cited by-同舟云学术

Rational Design of Bioorthogonally Activatable PROTAC for Tumor-Targeted Protein Degradation

Published:2023-10-23 Issue:21 Volume:66 Page:14843-14852
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bi Tao¹²,Liang Pan¹²,Zhou Yanan¹²,Wang Hong¹²,Huang Rui¹²,Sun Qin¹²,Shen Hongping¹²,Yang Sijin¹²,Ren Wei¹²,Liu Zengjin¹²^ORCID

Affiliation:

1. National Traditional Chinese Medicine Clinical Research Base and Drug Research Center of the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Chunhui Road, Luzhou 646000, China

2. Institute of Integrated Chinese and Western Medicine Southwest Medical University, Chunhui Road, Luzhou 646000, China

Funder

China Postdoctoral Science Foundation

Sichuan Provincial Administration of Traditional Chinese Medicine

State Administration of Traditional Chinese Medicine of the People's Republic of China

Sichuan Province Science and Technology Support Program

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c01423

Reference33 articles.

1. Protac-Induced Protein Degradation in Drug Discovery: Breaking the Rules or Just Making New Ones?

2. PROTACs: past, present and future

3. Advancing Strategies for Proteolysis-Targeting Chimera Design

4. Targeted protein degradation: expanding the toolbox

5. Discovery of Potent and Selective Epidermal Growth Factor Receptor (EGFR) Bifunctional Small-Molecule Degraders

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