PepScaf: Harnessing Machine Learning with In Vitro Selection toward De Novo Macrocyclic Peptides against IL-17C/IL-17RE Interaction

Author:

Zhai Silong1,Tan Yahong2,Zhang Chengyun1,Hipolito Christopher John3,Song Lulu2,Zhu Cheng1,Zhang Youming2,Duan Hongliang1,Yin Yizhen24ORCID

Affiliation:

1. School of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China

2. State Key Laboratory of Microbial Technology, Institute of Microbial Technology, Shandong University, Qingdao 266237, China

3. Screening & Compound Profiling, Quantitative Biosciences, Merck & Co., Inc., Kenilworth, New Jersey 07033, United States

4. Shandong Research Institute of Industrial Technology, Jinan 250101, China

Funder

Taishan Scholar Project of Shandong Province

Shandong University

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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