Exploring the Dispersion and Electrostatic Components in Arene–Arene Interactions between Ligands and G4 DNA to Develop G4-Ligands-Reference-Cited by-同舟云学术

Exploring the Dispersion and Electrostatic Components in Arene–Arene Interactions between Ligands and G4 DNA to Develop G4-Ligands

Published:2024-01-19 Issue:3 Volume:67 Page:2202-2219
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Andreasson Måns¹,Donzel Maxime¹,Abrahamsson Alva¹^ORCID,Berner Andreas²^ORCID,Doimo Mara²³,Quiroga Anna²,Eriksson Anna¹,Chao Yu-Kai⁴,Overman Jeroen⁴,Pemberton Nils⁵^ORCID,Wanrooij Sjoerd²,Chorell Erik¹^ORCID

Affiliation:

1. Chemical Biology Consortium Sweden, Department of Chemistry, Umeå University, 901 87 Umeå, Sweden

2. Departments of Medical Biochemistry and Biophysics, Umeå University, Umeå 90736, Sweden

3. Clinical Genetics Unit, Department of Women and Children’s Health, Padua University, 35128 Padua, Italy

4. Mechanistic and Structural Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge CB2 0AA, U.K.

5. Medicinal Chemistry, Research and Early Development, Respiratory and Immunology (R&I), Bio Pharmaceuticals R&D, AstraZeneca, Gothenburg SE-43183, Sweden

Funder

Vetenskapsr?det

Kempestiftelserna

Knut och Alice Wallenbergs Stiftelse

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c02127

Reference50 articles.

1. The Structure and Function of DNA G-Quadruplexes

2. The regulation and functions of DNA and RNA G-quadruplexes

3. Structure, properties, and biological relevance of the DNA and RNA G-quadruplexes: Overview 50 years after their discovery

4. Characterization of the Cation and Temperature Dependence of DNA Quadruplex Hydrogen Bond Properties Using High-Resolution NMR

5. Stability and kinetics of G-quadruplex structures